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I work with the Immunomodulation and Vaccines (I-VAC) Programme at the MRC/UVRI and LSHTM Uganda Research Unit. I am the trial statistician on the Entebbe Mother and Baby Study (EMaBS). This birth cohort, located in Entebbe, Uganda, investigates the impact of helminth infections and their treatment during pregnancy on birth outcomes, illness and allergy events during infancy, and on immunological responses to childhood vaccinations. I also co-lead the Co-Host study which is investigating the imapct of early-life and current exposures on responses to SARS-CoV-2 among EMaBS participants. I am a co-investigator on the POPVAC programme, which aims to understand population differences in vaccine response and to determine how vaccine effectiveness can be optimised for tropical low-income countries (LICs), based on trials in urban and rural populations in Uganda. I am co-investigator on the NIHR Global Health Research Group on Vaccines for Vulnerable people in Africa (VAnguard) which aims to identify structural, modifiable determinants of impaired vaccine impact in vulnerable communities and develop integrated strategies to address them.

I am trial statistician on the Praziquantel for Preschoolers (PIP) trial which aims to determine the optimal praziquantel dose for treatment of schistosomiasis among pre-school aged children in Uganda, and co-investigator on the MOBILE MEN study which is investigating implementation of CAB-LA and oral PrEP for prevention of HIV among mobile populations in Uganda and South Africa. I was trial statistician on the HomeACF Study, a household cluster randomised trial of active case finding for HIV and TB, preventive treatment against TB, and ART initiation to prevent TB disease and transmission, in South Africa. I am also the trial statistician for the ABAaNA early intervention trial, which investigates the feasibility and effectiveness of early intervention for young infants at high risk of neurodevelopmental delay and disability in Uganda.

I lead the EDCTP-funded ENTRANT fellowship scheme which is providing epidemiology and outbreak preparedness training to 15 public health practitioners from Botswana, Ethiopia, Kenya, Tanzania, Uganda and Zambia. I currently have doctoral students working on statistical modelling of vaccine responses among Uganda adolescents, the impact of malaria on SARS-CoV-2, the impact of fatty meal co-administration and double-dosing on albendazole effectivenesss, modeling integrated strategies to optimize vaccine impact among vulnerable populations in Uganda and Kenya, and the use of advanced statistical methods to assess survival and disease progression among participants with chronic obstructive pulmonary disease in low and middle income countries.