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Dr Clemence Leyrat

Associate Professor

London School of Hygiene and Tropical Medicine
Keppel Street
London
WC1E 7HT
United Kingdom

After studying cognitive sciences at the University of Bordeaux (France), I obtained a MSc in Biostatistics from the Bordeaux School of Public Health in 2010. Then, I moved to Tours (France) to do a PhD on the use of propensity score methods for the analysis of cluster randomised trials, under the direction of Prof Bruno Giraudeau. During this period, I developed a growing interest in causal inference methods to analyse observational data as well as for trial methodology. I joined the department of Medical Statistics in 2015, and since then, most of my research focussed on the use of causal inference methods developed for the analysis of real-world data to improve the design and analysis of trials, and the application of the rigorous methodology of trials to improve the transparency and quality of observational research.

Besides methodological research, I am involved in applied project with researchers from the Electronic Health Records group at LSHTM, and I have also been working closely with the Inequalities in Cancer Outcomes Network (Department of Health Services Research and Policy) on the application of causal inference methods, including emulated trials, to understand and tackle cancer inequalities in the UK.

Affiliations

Department of Medical Statistics
Faculty of Epidemiology and Population Health

Centres

Centre for Data and Statistical Science for Health

Teaching

Module organizer for:
- Causal Inference and Missing Data (MSc in Medical Statistics)

Face-to-Face teaching:
- Short course "Design & Analysis of Cluster Randomised and Stepped Wedge Trials"
- Short course "Essentials of Clinical Trials"
- Short course "Statistical Analysis with Missing Data Using Multiple Imputation"

I am a Fellow of the Higher Education Academy, and I hold the lecturer qualification from the French University Council.

Research

Causal inference
Trials methodology
Cancer epidemiology
Analysis of Electronic Health Record data
Research Area
Clinical trials
Modelling
Public health
Statistical methods
Epidemiology
Randomised controlled trials
Disease and Health Conditions
Cancer
Diabetes
Country
United Kingdom

Selected Publications

Besan莽on, L; Peiffer-Smadja, N; SEGALAS, C; Jiang, H; Masuzzo, P; Smout, C; Billy, E; Deforet, M; LEYRAT, C;
2021
BMC medical research methodology
LEYRAT, C; CARPENTER, JR; Bailly, S; WILLIAMSON, EJ;
2020
American journal of epidemiology
LEYRAT, C; Caille, A; Eldridge, S; Kerry, S; Dechartres, A; Giraudeau, B;
2018
International Journal of Epidemiology
LEYRAT, C; MORGAN, KE; LEURENT, B; Kahan, BC;
2018
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
LEYRAT, C; Seaman, SR; White, IR; DOUGLAS, I; SMEETH, L; KIM, J; Resche-Rigon, M; CARPENTER, JR; WILLIAMSON, EJ;
2017
Statistical methods in medical research
Caille, A; Kerry, S; Tavernier, E; LEYRAT, C; Eldridge, S; Giraudeau, B;
2016
BMJ (Clinical research ed)
LEYRAT, C; Caille, A; Foucher, Y; Giraudeau, B;
2016
BMC medical research methodology
LEYRAT, C; Caille, A; Donner, A; Giraudeau, B;
2014
Statistics in medicine
Caille, A; LEYRAT, C; Giraudeau, B;
2014
Statistical methods in medical research
Cucherat, M; Demarcq, O; Chassany, O; Le Jeunne, C; Borget, I; Collignon, C; Diebolt, V; Feuilly, M; Fiquet, B; LEYRAT, C; Naudet, F; Porcher, R; Schmidely, N; Simon, T; Roustit, M;
2024
Therapie