Since my PhD years I have been fascinated by the complexities and challenges of pneumococcal vaccination which has been one of my my main
foci of work. My research in this area is currently supported through a Sir Henry Dale Wellcome Trust Fellowship alongside other research
grants.
I have also been frequently following related interest, e.g. outbreak response (SARS-CoV-2, ebola and swine flu), antimicrobial resistance, vector bourne disease (dengue and malaria) and health in humanitarian crises.
I currently am a member of WHO's IVIR-AC and serve on a WHO SAGE's working groups on pneumococcal conjugate vaccines and on COVID19 vaccines. I also serve on the Joint Committee on Vaccination and Immunisation's (JCVI) pneumococcal subgroup.
Affiliations
Department of Infectious Disease Epidemiology and Dynamics
Faculty of Epidemiology and Population Health
Centres
Centre for Data and Statistical Science for Health
Centre for Mathematical Modelling of Infectious Diseases
Vaccine Centre
Antimicrobial Resistance Centre
Teaching
I teach on the modelling short course and the MSc module, on STEPH and ECCD and I co-organise and teach on the short course on epidemiological evaluation of vaccines. I supervise one to three Master student summer projects each year and a number of PhD projects; please get in touch if this is of interest to you.
Research
My main research area is the evaluation and optimisation of vaccine interventions. For S. pneumoniae this includes using mathematical models to help better understand how to use existing pneumococcal vaccine more efficiently, ie reducing cost and maximising impact, and to help designing optimal future vaccine formulations.
My team and I work closely with a range of international partners including on vaccine trials and their interpretation in Vietnam and in humanitarian crises settings. My other interests include real-time evaluation of pandemic pathogens as well as evolution and mitigation of AMR, assessing and
predicting the impact of vaccines against seasonal influenza, HiB, varicella zoster, melioidosis, non-typhoid salmonella, RSV, hand foot and mouth disease, malaria and dengue.
My team and I work closely with a range of international partners including on vaccine trials and their interpretation in Vietnam and in humanitarian crises settings. My other interests include real-time evaluation of pandemic pathogens as well as evolution and mitigation of AMR, assessing and
predicting the impact of vaccines against seasonal influenza, HiB, varicella zoster, melioidosis, non-typhoid salmonella, RSV, hand foot and mouth disease, malaria and dengue.
Selected Publications
2021
Wellcome Open Research
2021
Science (New York, N.Y.)
2019
LANCET INFECTIOUS DISEASES
2019
The Lancet. Infectious diseases
2019
The Lancet Global Health
2019
Nature ecology & evolution
2019
The Lancet Global Health
2018
The Lancet infectious diseases
2018
The Journal of infectious diseases
2024
The New England journal of medicine
